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Fig. 5 | BMC Ecology and Evolution

Fig. 5

From: Positive selection-driven fixation of a hominin-specific amino acid mutation related to dephosphorylation in IRF9

Fig. 5

Schematic molecular processes of the type I IFN signalling based on a literature review. The abbreviations and full names are IFNAR1 (Interferon Alpha and Beta Receptor Subunit 1), IFNAR2 (Interferon Alpha and Beta Receptor Subunit 2), TYK2 (Tyrosine Kinase 2), JAK (Janus kinase), STAT1 (Signal Transducer and Activator Of Transcription 1), STAT2 (Signal Transducer And Activator Of Transcription 2), ISRE (IFN stimulated response elements), and ISGs (interferon-stimulated genes)

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