Fig. 3
From: Insertion/deletion hotspots in the Nsp2, Nsp3, S1, and ORF8 genes of SARS-related coronaviruses
Multiple sequence alignment in the N-terminal domain of S1 gene
Distribution of indels in the N-terminal domain of the S1 gene in the five SARS-related coronaviruses is shown. Based on the frequency and length of the indels, this domain is regarded as another site of indel hotspots. The frequency of indels in the N-terminal domain is significantly higher than that in the receptor-binding domain
S, spike; SARS-CoV, severe acute respiratory syndrome coronavirus