Fig. 1
From: Insertion/deletion hotspots in the Nsp2, Nsp3, S1, and ORF8 genes of SARS-related coronaviruses
Distribution of point mutation rate and indels in the genomes of PCoV_GX-P4L and SARS-CoV-2
The base position-oriented point mutation rate, together with the locations of indels (solid bars), across the genomes of PCoV_GX-P4L and SARS-CoV-2 are shown, compared with the reference genome of SARS-CoV from 2002–2003. The point mutation rate was calculated as the rolling average of the point mutation rate in the nearest ± 50 bases at each base position after excluding the base positions with indels. The blue areas around the line graphs represent 95% confidence intervals for the point mutation rates. Indels were categorized into the following three general types: insertions (blue bar), deletions (red bar), and deletions-with-insertions (black bar). The width of each bar is proportional to the length of the consecutive bases involved in each indel site
E, envelope; M, membrane; N, nucleocapsid; ORF, open reading frame; PCoV_GX-P4L, pangolin coronavirus GX-P4L; S, spike; SARS-CoV, severe acute respiratory syndrome coronavirus