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Table 3 The output of Cox proportional hazards models for coevolving pathogens from different populations when they infect their sympatric as well as allopatric hosts

From: Drosophila melanogaster hosts coevolving with Pseudomonas entomophila pathogen show sex-specific patterns of local adaptation

Summary of Cox proportional hazards model

PATHOGEN 1 (B1Pe)

   

Fixed coefficients

Hazard ratio

Lower CL

Upper CL

Female

   

TypeSympatric

0.5014

0.3601

0.6981

Random effects

   

Group

Variance

  

Replicate/Type

0.00018

  

Replicate

0.00039

  

Male

   

TypeSympatric

0.2307

0.1654

0.3217

Random effects

   

Group

Variance

  

Replicate/Type

0.0004

  

Replicate

0.1322

  

PATHOGEN 2 (B2Pe)

   

Fixed coefficients

Hazard ratio

Lower CL

Upper CL

Female

   

TypeSympatric

0.37262

0.2679

0.5181

Random effects

   

Group

Variance

  

Replicate/Type

0.0004

  

Replicate

0.00039

  

Male

   

TypeSympatric

0.2786

0.1468

0.5288

Random effects

   

Group

Variance

  

Replicate/Type

0.3316

  

Replicate

0.1584

  

PATHOGEN 3 (B3Pe)

   

Fixed coefficients

Hazard ratio

Lower CL

Upper CL

Female

   

TypeSympatric

0.7746

0.4986

1.203

Random effects

   

Group

Variance

  

Replicate/Type

 < 0.0001

  

Replicate

 < 0.0001

  

Male

   

TypeSympatric

0.788

0.5793

1.071

Random effects

   

Group

Variance

  

Replicate/Type

 < 0.0001

  

Replicate

 < 0.0001

  

PATHOGEN 4 (B4Pe)

   

Fixed coefficients

Hazard ratio

Lower CL

Upper CL

Female

   

TypeSympatric

1.1552

0.7992

1.669

Random effects

   

Group

Variance

  

Replicate/Type

0.00039

  

Replicate

0.00012

  

Male

   

TypeSympatric

0.9983

0.6847

1.4554

Random effects

   

Group

Variance

  

Replicate/Type

 < 0.0001

  

Replicate

 < 0.0001

  
  1. Hazard rates are expressed relative to the hazard rates of the default level of the fixed factor, which is constrained to be 1. The default level for “Host Type” is Allopatric treatment. Lower CL and Upper CL indicate lower and upper bounds of 95% confidence intervals. Confidence intervals that do not contain 1 signify statistical significance and are shown in bold. Higher hazard rates are equivalent to lower survivorship in the hosts