Fig. 10

Summary of distribution of Wnt orthologs in metazoan genomes. “X” in white boxes indicates the loss of a Wnt gene. “?” in white boxes indicates that a fully sequenced genome is unavailable for the associated lineage, so it is unclear whether the ortholog has been lost, or is present, but unsequenced. Gray boxes associated with Hofstenia indicate unclear orthology of the four Wnt genes found in the genomes of representatives of this lineage. Dashed lines coming off of Hofstenia represent different hypotheses of the relationship of this lineage with other bilaterians. The interrelationships of panarthropod phyla (Arthropoda, Onychophora, Tardigrada) are depicted as a polytomy because they are not currently resolved [69]. Arthropoda = Drosophila–Ixodes; Onychophora = Euperipatoides; Hypsibius–Ramazzottius = Tardigrada