Table 1 Terminology used throughout text
Term | Meaning |
|---|---|
MSA | Acronym for multiple sequence alignment |
Dataset | A set of unaligned orthologous sequences |
Datatype | Either nucleotide (NT) or amino-acid (AA) |
Dataset source | Either Drosophila, Euteleostomi, or PANDIT |
Reference MSA | The initial MSA created from a given dataset using default MAFFT settings |
Perturbed MSA | A perturbed MSA generated from a given dataset using a GUIDANCE2-based approach |
Variant MSA | One of any 50 unique MSAs (either reference or variant MSA) built from a given dataset |
Stable dataset | A dataset with the same selected model for all variant MSAs |
Unstable dataset | A dataset with at least two distinct selected models among all variant MSAs |
\({M_0}\) | The most frequently identified best-fitting model for a given dataset |
\({M_{\text{ref}}}\) | The best-fitting model identified for a given dataset’s reference MSA |