Fig. 2
From: The evolution of the metazoan Toll receptor family and its expression during protostome development
Review of the number of TLRs across metazoans. Within metazoans, no TLRs have been found outside Cnidaria and Bilateria. Spiralians show a variable number of TLRs, being, for example, 23 TLRs in the annelid C. teleta, but none in the rotifer A. vaga. In ecdysozoans, C. elegans and D. melanogaster have 1 and 9 TLRs, respectively. The number of TLRs in deuterostomes is also variable, being high in S. purpuratus and B. lanceolatum, but reduced in tunicates. References: [8, 11, 18, 27, 52, 64,65,66, 69, 70, 72, 75, 82, 84, 88, 92, 94, 96, 97]. Phylogeny according to [98]