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Table 2 Effect of fertility selection, distortion and viability selection on mating rates and offspring proportions. Fertility selection changes the mating rate of genotypes at adult stage. Distortion biases the transmission of drive allele from heterozygous individual by probability p > 0.5. Each entry in offspring’s column gives the proportion of genotype produced from the mating pair in the corresponding row. Viability selection effects offspring proportions as some may become non-viable. To illustrate an example, we consider Medea gene drive where wild-type homozygous offspring of heterozygous mother are non-viable.

From: A common gene drive language eases regulatory process and eco-evolutionary extensions

Fertility Selection

Distortion

Viability Selection (e.g., Medea)

♂

♀

Fertilities

WW

WD

DD

WW

WD

DD

WW

WW

\(f_{WW}.f_{WW}\)

1.0

  

1.0

  

WW

WD

\(f_{WW}.f_{WD}\)

\((1-p)\)

p

 

\(0.5 (1-d_m)\)

\(0.5 \omega\)

 

WW

DD

\(f_{WW}.f_{DD}\)

 

1.0

  

\(1.0 \omega\)

 

WD

WW

\(f_{WD}.f_{WW}\)

\((1-p)\)

p

 

0.5

\(0.5 \omega\)

 

WD

WD

\(f_{WD}.f_{WD}\)

\((1-p)^2\)

\(2p(1-p)\)

\(p^2\)

\(0.25 (1-d_m)\)

\(0.5 \omega\)

\(0.25 \nu\)

WD

DD

\(f_{WD}.f_{DD}\)

 

\((1-p)\)

p

 

\(0.5 \omega\)

\(0.5 \nu\)

DD

WW

\(f_{DD}.f_{WW}\)

 

1.0

  

\(1.0 \omega\)

 

DD

WD

\(f_{DD}.f_{WD}\)

 

\((1-p)\)

p

 

\(0.5 \omega\)

\(0.5 \nu\)

DD

DD

\(f_{DD}.f_{WD}\)

  

1.0

  

\(1.0 \nu\)