Genetic mapping of metabolic traits in the blind Mexican cavefish reveals sex-dependent quantitative trait loci associated with cave adaptation

Table 1 Average values for surface/Pachón F2 traits

Trait	Male	N	female	N	t-test_pval	wilcox_pval
Weight start (g)	1.58	100	3.53	119		1.08E−19
Weight 4 month (g)	1.73	95	3.33	115		1.07E−18
Length start (cm)	4.38	99	5.18	117	2.10E−13
Length end (cm)	4.43	91	5.10	108	4.09E−12
Body condition start	1.83	97	2.35	116		4.03E−18
Body condition end	1.92	89	2.35	106		2.21E−15
Weight change (g)	0.14	96	− 0.23	117		5.60E−05
% weight change	14.70	95	0.13	115		4.99E−06
Gonad weight (g)	0.06	80	0.42	100		1.29E−24
Weight minus gonad (g)	1.65	81	2.91	100		4.72E−13
Gonad weight/weight	0.03	80	0.13	60		1.14E−20
Blood glucose start (mg/dL)	41.10	48	41.23	111		7.68E−01
Blood glucose end (mg/dL)	60.76	84	59.28	84		4.13E−01
Blood glucose change (mg/dL)	13.41	70	7.55	105		2.68E−01
Arginine blood glucose (mg/dL)	58.46	88	61.26	104		7.08E−01
Arginine response	19.97	69	23.93	50	6.25E−01
Muscle triglyceride	0.19	83	0.20	102		7.67E−01
Visceral fat area (cm³)	0.21	88	0.27	108		7.67E−01
Liver area (cm³)	0.31	88	0.50	108		6.67E−12
Midgut length (cm)	1.43	83	1.66	102	2.73E−05
Hindgut length (cm)	0.64	87	0.78	107		6.77E−08
Liver area/fish length	0.07	87	0.10	107	7.36E−10
Midgut length/fish length	0.32	70	0.33	84	5.00E−01
Hindgut length/fish length	0.14	44	0.15	44	3.20E−02

Traits that are significantly different between sexes in bold. Students t-test used for normally distributed traits and Wilcox test used for non-normally distributed traits based on Shapiro–Wilks test. Adjusted false discovery rate p-value is shown [65]

ISSN: 2730-7182