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Table 1 Enrichments in CNS region-specific genes for the tested and reference gene groups

From: Region-specific expression of young small-scale duplications in the human central nervous system

Reference groupa

Tested group for CNS region-specificitya

Percentage of CNS region-specific genes in the tested group (%)

Chi-squared test P-valueb

Odds ratioc

Protein coding genes

Paralogous genes

19.2

2.045E−18*

1.48

Paralogous genesd

WGD genes

15.7

1.061E−18*

0.64

SSD genes

22.6

9.022E−11*

1.39

ySSD genes

28.6

6.341E−18*

1.82

SSD genes

ySSD genes

28.6

3.483E−09*

1.62

oSSD genes

15.6

2.729E−13*

0.52

WGD + wSSD genes

wSSD genes

24.0

5.185E−12*

1.69

  1. aAbbreviations for gene duplication categories: WGD (Whole-Genome Duplication), SSD (Small-Scale Duplication), ySSD (younger SSD occuring after WGD events), oSSD (older SSD occuring before WGD events) and wSSD (WGD-old SSD occuring around WGD events)
  2. bApplication of Chi-squared tests (or of Fisher’s exact test when the Chi-squared test could not be applied) with a corrected p-value threshold = 7.14E-03 (Bonferroni correction for 7 statistical tests)
  3. cThe odds ratio (> 1 or < 1) indicates the group (tested or non-tested respectively) in which there is an enrichment
  4. dThe paralog reference group includes the genes belonging to WGD, SSD and WGD-SSD categories and the paralogs without annotation
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BMC Ecology and Evolution

ISSN: 2730-7182

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