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Table 2 Genes identified as evolving under positive selection

From: Positive natural selection in primate genes of the type I interferon response

Induction genes evolving under positive selection Interferon-stimulated genes evolving under positive selection
CASP10 ADAR*
CIITA* APOBEC3F
CISH APOBEC3G*
DDX58* APOL2*
DDX60* APOL6*
EPOR BST2*
IFI16* CCL8
IFNAR1* CD47
IFNAR2 CEACAM1
MAVS* CRP
MB21D1* DAPK1
MNDA EIF2AK2*†
OAS1* GBP2*
OAS2* IFI27
PTPRC IFI44
PYHIN1 IFI44L
RNASEL* IFI6
SPP1 IFIT1*
STAT2* IFIT2*
TLR1* MLKL
TLR2* MX1*
TLR4* MX2*
TLR5* PHF11
TLR6* RSAD2*
TLR8* RTP4*
TMEM173* SAMD9
TRIM21* SAMHD1*
TRIM25* SLFN12*
TYK2 TAGAP
  TMEM140
  TNK2
  TRIM22*
  TRIM5*
  ZC3HAV1*
  1. Genes that have been previously identified as rapidly evolving in primates (*) and which genes have known interactions with pathogenic elements () are from the following studies: [27, 42, 49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64]
  2. * Previously identified as being under positive selection in primates
  3. † Published interaction with pathogen