Table 1 Corallium rubrum proteins identified in the axial skeleton and the sclerites

CR_1

TRINITY_DN57230_c0_g1_i1

Scleritin (UOMP)

CR_2

TRINITY_DN62338_c1_g1_i2

Sushi domain-containing 2-like

Mucin

CR_3_4

scaff2294:c99220-62,422

CAP-like

CAP

Yes

CR_5

TRINITY_DN53149_c0_g1_i1

Collagen triple helix repeat

Collagen

Yes

CR_6

TRINITY_DN55882_c0_g1_i1

Fibrinogen-related

CR_7

TRINITY_DN63002_c0_g1_i7

Low-density lipo receptor-related like 4

LRP

CR_8

TRINITY_DN56567_c4_g1_i4

UOMP

Yes

CR_9

TRINITY_DN52968_c0_g1_i1

Collagen α -1(V) chain

Collagen

Yes

CR_10_28_60

scaff2907:c1055600-1,011,000

Agrin-1

Agrin

Yes

CR_11

TRINITY_DN58426_c1_g1_i1

?

CR_12

TRINITY_DN58029_c4_g3_i1

Tyrosinase

CR_13

TRINITY_DN58119_c0_g1_i1

?

CR_14

TRINITY_DN62074_c1_g1_i7

Galaxin (UOMP)

Galaxin

CR_15

TRINITY_DN63296_c1_g4_i3

Melanotransferrin-like

CR_16

TRINITY_DN56632_c0_g3_i1

MMP12A

Peptidase (zinc)

CR_17

TRINITY_DN52633_c0_g1_i1

Collagen α -1(XI) chain

Collagen

CR_18

TRINITY_DN62446_c0_g1_i1

?

CR_19

TRINITY_DN51464_c0_g1_i1

Agrin

Agrin

CR_20

TRINITY_DN57322_c0_g1_i1

MMP12B

PEPTIDASE (zinc)

CR_21

TRINITY_DN52133_c0_g1_i1

NA

Sugar-binding

Yes

CR_22

TRINITY_DN60196_c2_g6_i1

?

Sugar-binding

Yes

CR_23

TRINITY_DN61543_c0_g1_i1

Plexin domain-containing protein

CR_24

TRINITY_DN64090_c0_g1_i6

Protocadherin like

Protocadherin

CR_25

TRINITY_DN58830_c0_g1_i1

NA

Frizzled domain

Yes

CR_26

TRINITY_DN58830_c0_g4_i2

NA

Frizzled domain

Yes

CR_27

TRINITY_DN61967_c0_g2_i2

Galaxin (UOMP)

Galaxin

CR_29

TRINITY_DN45133_c0_g1_i1

CruCA4

CR_30

TRINITY_DN63986_c2_g1_i1

Peptidase S8

Peptidase (serine)

CR_31

TRINITY_DN48716_c1_g1_i1

NA

Yes

CR_32

TRINITY_DN63619_c0_g1_i8

?

CR_33

TRINITY_DN55669_c0_g3_i8

UOMP

Yes

CR_34

TRINITY_DN63069_c2_g1_i2

Protocadherin Fat 4

Protocadherin

CR_35

TRINITY_DN58620_c3_g1_i1

Collagen α -1(III) chain

Collagen

Yes

CR_36

TRINITY_DN62341_c4_g3_i7

NA

Yes

CR_37

TRINITY_DN56000_c0_g2_i3

UOMP

Yes

CR_38

TRINITY_DN54322_c0_g1_i1

Collagen α -2(I) chain

Collagen

Yes

CR_39

TRINITY_DN53417_c0_g1_i4

Collagen α -1(VI) chain

Collagen

Yes

CR_40

TRINITY_DN62648_c2_g1_i1

Transmembrane protease serine 9

GliPR

CR_41

TRINITY_DN41663_c0_g1_i1

Exostosin-3

GAG_elongation

CR_42

TRINITY_DN63404_c0_g2_i1

Peptidyl-glycine α -amidating monooxygenase

PAL_PHM_PAM

CR_43

TRINITY_DN48082_c0_g1_i1

Renin receptor

CR_44

TRINITY_DN51483_c0_g1_i1

V-type proton ATPase subunit S1-like

CR_45

TRINITY_DN63929_c2_g1_i5

Pentraxin

Sugar-binding

CR_46

TRINITY_DN63365_c0_g1_i3

Peptidyl-α-Hydroxyglycine α-amidating lyase

PAL_PHM_PAM

CR_47

TRINITY_DN62037_c1_g1_i1

NA

Sugar-binding

Yes

CR_48

TRINITY_DN63397_c3_g1_i3

UOMP

Yes

CR_49

TRINITY_DN61472_c0_g2_i3

Cytoplasmic Actin

CR_50

TRINITY_DN60827_c2_g2_i3

Collagen α -2(V) chain

Collagen

CR_51

TRINITY_DN63041_c1_g1_i2

Complement component C3 precursor

CR_52

TRINITY_DN63149_c1_g3_i3

Cystatin

Peptidase inhibitor

CR_53

TRINITY_DN58234_c0_g2_i1

Agrin

Agrin

CR_54

TRINITY_DN61441_c0_g1_i3

Collagen α -1(II) chain isoform X2

Collagen

CR_55

TRINITY_DN51187_c0_g2_i2

UOMP

CR_56

TRINITY_DN63166_c7_g6_i1

Collagen α -1(I) chain-like

Collagen

CR_57

TRINITY_DN54300_c1_g1_i1

Pentraxin

Sugar-binding

CR_58

TRINITY_DN58073_c0_g1_i1

Pikachurin-like

Sugar-binding

CR_59

TRINITY_DN64032_c0_g1_i3

α -2-Macroglobulin 1 isoform X2

CR_62_76_82

scaff2512:c157700-123,800

Agrin-2

Agrin

Yes

CR_61

TRINITY_DN61195_c0_g1_i1

MMP13

Peptidase (zinc)

CR_63

TRINITY_DN45588_c0_g1_i1

Tenascin-like

CR_64

TRINITY_DN63439_c12_g3_i1

MMP12A

Peptidase (zinc)

CR_65

TRINITY_DN56377_c0_g1_i2

CUB and sushi Domain-containing 3

Sugar-binding

CR_66

TRINITY_DN51686_c0_g1_i1

Superoxide dismutase [Cu–Zn]

CR_67

TRINITY_DN58794_c0_g8_i1

UBA52

CR_68

TRINITY_DN63204_c1_g1_i3

Collagen α -1(I) chain

Collagen

CR_69

TRINITY_DN63340_c1_g2_i1

Zinc transporter ZIP14

CR_70

TRINITY_DN62875_c0_g2_i2

Protein kinase C-binding protein NELL1

Sugar-binding

CR_71

TRINITY_DN43523_c0_g1_i1

?

CR_72

TRINITY_DN53651_c2_g1_i1

UOMP

CR_73

TRINITY_DN30803_c0_g2_i1

Calumenin

EFh_CREC_cab45

CR_74

TRINITY_DN53562_c0_g1_i1

Bactericidal permeability-increasing-like

CR_75

TRINITY_DN39424_c0_g1_i1

UOMP

Yes

CR_77

TRINITY_DN62341_c4_g3_i6

NA

Yes

CR_78

TRINITY_DN58182_c1_g1_i1

UOMP

CR_79

TRINITY_DN61728_c0_g3_i8

Sialate O-acetylesterase

CR_80

TRINITY_DN56386_c0_g1_i1

UOMP

CR_81

TRINITY_DN61964_c1_g1_i4

Cathepsin Z

Peptidase (cysteine)

CR_83

TRINITY_DN56964_c4_g1_i1

Thrombospondin-type laminin G domain and EAR repeat-containing protein

CR_84

TRINITY_DN54518_c0_g1_i3

NA

Yes

CR_85

TRINITY_DN63555_c0_g1_i5

?

Sugar-binding

Yes

CR_86

TRINITY_DN43665_c0_g1_i1

45 kDa calcium-binding

EFh_CREC_cab45

CR_87

TRINITY_DN63601_c0_g1_i2

Transforming growth factor-β-induced ig-h3-like

CR_88

TRINITY_DN19382_c0_g1_i1

UOMP

Yes

CR_89

TRINITY_DN55648_c0_g1_i2

?

CR_90

TRINITY_DN62899_c0_g1_i1

Peptidase S9

Peptidase (serine)

CR_91

TRINITY_DN37336_c0_g1_i1

UOMP

Yes*

CR_92

TRINITY_DN60582_c0_g1_i2

Haem peroxidase

Haem peroxidase

CR_93

TRINITY_DN30927_c0_g2_i1

Prolyl 4-hydroxylase-like

P4H

CR_94

TRINITY_DN57626_c0_g3_i10

UOMP

Yes

CR_95

TRINITY_DN58599_c0_g1_i3

?

Yes

CR_96

TRINITY_DN12946_c0_g1_i1

Gamma-glutamyl-transpeptidase

CR_97

TRINITY_DN55829_c0_g1_i3

NA

Sugar-binding

Yes

CR_98

TRINITY_DN57865_c0_g2_i3

von Willebrand factor, type A

CR_99

TRINITY_DN64024_c5_g1_i3

Histone H4

CR_100

TRINITY_DN59633_c0_g1_i1

Adhesion G-coupled receptor D1

CR_101

TRINITY_DN55506_c0_g1_i1

Low-density lipo receptor-related 6

LRP

CR_102

TRINITY_DN36837_c0_g1_i1

Histone H2B type 2-E-like

CR_103

TRINITY_DN53166_c0_g1_i1

UOMP

Yes

CR_104

TRINITY_DN61990_c1_g1_i7

NA

Yes

CR_105

TRINITY_DN55043_c0_g1_i2

UOMP

CR_106

TRINITY_DN59627_c2_g1_i13

UOMP

Yes

CR_107

TRINITY_DN61728_c0_g3_i1

Sialate O-acetylesterase