Fig. 3
From: Mitochondrial-nuclear coadaptation revealed through mtDNA replacements in Saccharomyces cerevisiae
Evidence for mitonuclear coadaptation. For each nuclear background, growth rates of strains containing parental and synthetic mitonuclear genotypes were compared using one-way ANOVAs. Genotypes are connected by colored lines to indicate when the original, coadapted genotype showed fitness advantages (red) or disadvantages (black) as compared to the synthetic genotype (P < 0.05). Non-significant growth differences are shown by light gray lines. Growth rates were normalized to the parental mitonuclear genotype for presentation purposes. Strains were tested in ecologically-relevant media at 30 °C including a. fermentation isolates in SGM; b. oak, soil, and laboratory isolates in SOE, SGM and CSM/CSMEG, respectively; C. clinical isolates belonging to the Wine/European clade in SGM at 30 °C and 37 °C