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Fig. 2 | BMC Evolutionary Biology

Fig. 2

From: Mitochondrial-nuclear coadaptation revealed through mtDNA replacements in Saccharomyces cerevisiae

Fig. 2

Genetic distance influences the effect of mitonuclear interactions. a. All possible mtDNA exchanges among strains with clean (non-mosaic) lineages. Significant mitonuclear epistasis was expected to result from mtDNA exchange between two strains from different subpopulations (red solid lines), but not from mtDNA exchanges within a subpopulation (dark gray dotted lines). b. Frequencies of significant mitonuclear epistasis within and between clades. (see Table S9 for exact numbers). c. Mitonuclear effect sizes were significantly different in 4 conditions. Between clade mtDNA exchanges (red) often resulted in stronger epistatic effects (ΔΔ) than within clade exchanges (dark gray). ΔΔ = ∣(ΔnDNAi/mtDNAi→nDNAi/mtDNAj) – (ΔnDNAj/mtDNAi→ nDNAj/mtDNAj) ∣; * P < 0.05, ** P < 0.005

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