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Fig. 2 | BMC Evolutionary Biology

Fig. 2

From: Molecular evolutionary and structural analysis of human UCHL1 gene demonstrates the relevant role of intragenic epistasis in Parkinson’s disease and other neurological disorders

Fig. 2

Domains organization of UCHL1 protein. a Diagrammatic representation of UCHL1 domains and motifs. Schematic view of comparative organization of domains and motifs of UCHL1 orthologous proteins from phylogenetically distant species. Protein and domain lengths are drawn approximately to scale. Domains and motifs are color coded. Numbers on the scale represents amino acids. b Plot depicts those amino acid sites of UCHL1 which are under negative selection constraint in sarcopterygians. X-axis depicts site index of each residue of UCHL1 and y-axis depicts dN-dS rate analysis of each amino acid residue of UCHL1

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