Skip to main content

Table 4 Ordering of the MHC loci based on decreasing values of three genetic diversity indexes in chimpanzees (pooled cohort) and humans (average on multiple populations)

From: Similar patterns of genetic diversity and linkage disequilibrium in Western chimpanzees (Pan troglodytes verus) and humans indicate highly conserved mechanisms of MHC molecular evolution

Genetic diversity

Species

Ordering of values

Allelic richness

Chimpanzees (pooled cohort&)

B > A > C > DRB1 > DPB1 > DQB1 > DQA1

Humans (average#)

B > DRB1 > C > A > DPB1 > DQB1 > DQA1

Heterozygosity

Chimpanzees (pooled cohort&)

A > B > DRB1 > C > DPB1 > DQA1 > DQB1

Humans (average#)

B > DRB1 > C > A > DQB1 > DQA1 > DPB1

Nucleotide diversity

Chimpanzees (pooled cohort&)

DQA1 > DRB1 > B > DQB1 > A > C > DPB1

Humans (average#)

DRB1 > DQA1 > DQB1 > B > A > C > DPB1

  1. Perfect matches in locus ordering between chimpanzees and humans are highlighted in bold; # estimated on multiple human populations; &: for chimpanzees, the pooled cohort has an average sample size of 45.57 on the different loci; #: for humans, the averages were calculated on an average number of 70.14 populations with an average sample size of 109.46. The pooled cohort does not include Texascb (see Text)
Back to article page

BMC Ecology and Evolution

ISSN: 2730-7182

Contact us