Fig. 5
From: Distinct evolutionary trajectories of V1R clades across mouse species
Example receptor groups depicting patterns of lineage-specific evolution and conservation across clades. V1R annotations are abbreviated (e.g. Vmn1r137 as 137). Species transcripts annotated with the same reference gene have unique transcript IDs (e.g. 217.1 and 217.2). Mus species are indicated with colors and letters (M. m. domesticus: “m” and black; M. spicilegus: “z” and blue; M. macedonicus: “x” and red; M. spretus: “s” and orange; M. caroli: “c” and green; M. pahari: “p” and purple). a Clade H: entire clade shown, highlighting receptor groups that depict patterns of conservation and divergence. b Clade C: sub-clades shown with percentages of non-orthologous receptors. Vmn1r7/8 and Vmn1r9/10 are shown in detail. c Clade D: specific clade D receptor groups uniquely conserved across species. d-e Clade E: Specific receptor subregions of clade E. Highlighted receptors have some functional evidence (grey) or are deorphanized with strong evidence (red). f Clade J/K: entire clade depicted, highlighting specific deorphanized receptor groups that detect estrus cues (sulfated estrogens) in female urine