From: Recurrent sequence evolution after independent gene duplication
P | Fate ‘yellow’ | Fate ‘blue’ | Common denominator | Potential differentiation |
---|---|---|---|---|
20 | eef-1B.1 (Cele) | eef-1B.2 (Cele) | elongation factor | - |
19 | cka1 (Scer) | cka2 (Scer) | casein kinase II, catalytic subunit | i.a. Specific protein interactions [36] |
19 | vma11 (Scer) | vma3 (Scer) | V-ATPase subunit | Complementary loss of interaction interfaces [34] |
18 | ercc3 (Gthe) | unknown | TFIIH subunit XPB | - |
17 | Hspa2 | Hspa8 | heat-shock protein | Constitutive vs. heat-induced expression [30] |
16 | RpIIIc160 (Dmel) | unknown | DNA-directed RNA polymerase subunit | - |
15 | Rrm2 | Rrm2b | ribonucleotide reductase regulatory subunit | Complexes specialized to cell-cycle progression vs. DNA repair [35] |
15 | Sphk1 | Sphk2 | sphingosine kinase | Antagonists in sphingolipid metabolism? [37]. |
15 | eno1 (Xtro) | eno4 (Xtro) | enolase | - |
14 | aspS1 (Ddis) | aspS2 (Ddis) | aspartate–tRNA ligase | - |
14 | unknown | unknown | ethanolaminophosphotransferase | - |
13 | Senp6 | Senp7 | sentrin-specific protease | Some substrate specificity and differences in catalytic activity [38] |
13 | Mpdu1 | Pqlc3 | ∼ cargo receptors | - |
13 | unknown | unknown | isoleucine–tRNA ligase | - |
13 | Hars | Hars2 | histidine–tRNA ligase | Cytoplasmic vs. mitochondrial specialization [32] |
12 | rpa1 (Gthe) | rpa1 (Gthe) | replication protein A1 | - |
12 | unknown | unknown | cystinosin | - |
12 | nmd3 (Gthe) | nmd3 (Gthe) | 60S ribosomal export protein NMD3 | - |
12 | Sco1 | Sco2 | synthesis of cytochrome c oxidase | - |
12 | cycs (Xtro) | cyct (Xtro) | cytochrome c | Somatic vs. testis-specific in animals [39] |
12 | aimp1 (Drer) | aimp1 (Drer) | ARS-interacting multifunctional proteina | - |
12 | psenA (Ddis) | psenB (Ddis) | presinilin | - |