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Table 1 Results of the aBSREL analysis with the ω distribution over the sites of the human testis-enriched genes with corrected and uncorrected p-values (in bold, the significant test p-value). The gene ontology terms (GO) are also given

From: Population-specific, recent positive directional selection suggests adaptation of human male reproductive genes to different environmental conditions

Gene

Chr

Gene description

GO molecular/GO biological

Test p-value

Uncorrected p-value

ω distribution over sites

SPATA16

3

Spermatogenesis associated 16

Spermatogenesis GO:0007283

Cell differentiation GO:0030154

0.21

0.019

ω1 > 1000 (100%)

C9orf43

9

Chromosome 9 open reading frame 43

Protein binding GO:0005515

0.21

0.026

ω1 > 1000 (100%)

C9orf131

9

Chromosome 9 open reading frame 131

No data available

0.11

0.012

ω1 = 7.19 (100%)

ZFAND4

10

Zinc finger AN1-type containing 4

Zinc ion binding GO:0008270

0.55

0.05

ω1 = 1000 (100%)

C12orf40

12

Chromosome 12 open reading frame 40

Protein binding GO:0005515

0.35

0.032

ω1 > 1000 (100%)

TMCO5A

15

Transmembrane and coiled-coil domains 5A

No data available

0.4

0.036

ω1 > 1000 (100%)

NACA2

17

Nascent polypeptide associated complex alpha subunit 2

Protein transport GO:0015031

0.4

0.044

ω1 > 1000 (100%)

TULP2

19

Tubby like protein 2

Phosphatidylinositol binding GO:0035091

Protein-containing complex binding GO:0044877

Protein localization to cilium GO:0061512

Protein localization to photoreceptor outer segment GO:1903546

Visual perception GO:0007601

0.027

0.002

ω1 = 0.00 (98%)

ω2 = 1290 (1.5%)

FAM209A

20

Family with sequence similarity 209 member A

No data available

0.07

0.008

ω1 = 0.00 (96%)

ω2 = 1350 (4.0%)

POTED

21

POTE ankyrin domain family member D

Actin binding GO:0003779

Actin cytoskeleton organization GO:0030036

0.098

0.011

ω1 > 1000 (100%)

MAGEB16

X

MAGE family member B16

No data available

0.4

0.044

ω1 = 0.00 (97%)

ω2 = 42.3 (3.3%)