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Table 1 Results of the aBSREL analysis with the ω distribution over the sites of the human testis-enriched genes with corrected and uncorrected p-values (in bold, the significant test p-value). The gene ontology terms (GO) are also given

From: Population-specific, recent positive directional selection suggests adaptation of human male reproductive genes to different environmental conditions

Gene Chr Gene description GO molecular/GO biological Test p-value Uncorrected p-value ω distribution over sites
SPATA16 3 Spermatogenesis associated 16 Spermatogenesis GO:0007283
Cell differentiation GO:0030154
0.21 0.019 ω1 > 1000 (100%)
C9orf43 9 Chromosome 9 open reading frame 43 Protein binding GO:0005515 0.21 0.026 ω1 > 1000 (100%)
C9orf131 9 Chromosome 9 open reading frame 131 No data available 0.11 0.012 ω1 = 7.19 (100%)
ZFAND4 10 Zinc finger AN1-type containing 4 Zinc ion binding GO:0008270 0.55 0.05 ω1 = 1000 (100%)
C12orf40 12 Chromosome 12 open reading frame 40 Protein binding GO:0005515 0.35 0.032 ω1 > 1000 (100%)
TMCO5A 15 Transmembrane and coiled-coil domains 5A No data available 0.4 0.036 ω1 > 1000 (100%)
NACA2 17 Nascent polypeptide associated complex alpha subunit 2 Protein transport GO:0015031 0.4 0.044 ω1 > 1000 (100%)
TULP2 19 Tubby like protein 2 Phosphatidylinositol binding GO:0035091
Protein-containing complex binding GO:0044877
Protein localization to cilium GO:0061512
Protein localization to photoreceptor outer segment GO:1903546
Visual perception GO:0007601
0.027 0.002 ω1 = 0.00 (98%)
ω2 = 1290 (1.5%)
FAM209A 20 Family with sequence similarity 209 member A No data available 0.07 0.008 ω1 = 0.00 (96%)
ω2 = 1350 (4.0%)
POTED 21 POTE ankyrin domain family member D Actin binding GO:0003779
Actin cytoskeleton organization GO:0030036
0.098 0.011 ω1 > 1000 (100%)
MAGEB16 X MAGE family member B16 No data available 0.4 0.044 ω1 = 0.00 (97%)
ω2 = 42.3 (3.3%)