Fig. 2

Episodes of diversifying positive selection on three genes from the RCA cluster, including Zp3r and C4bpa (in Glires), and C4BPA (in Primates). Zp3r and C4BPA are known or expected to be expressed in gametes and sensitive to sexual selection, but C4bpa is not. Red branches in each phylogeny show lineages under positive selection in aBSREL analyses. Numbered red vertical bars in each gene cartoon show the locations of codons under positive selection in MEME analyses relative to the total length of the alignment (the grey bar), and relative to several different protein coding domain types. No episodes of diversifying selection were found in C4bpb (in Glires) or C4BPB (in Primates; not shown)