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Fig. 8 | BMC Evolutionary Biology

Fig. 8

From: On estimating evolutionary probabilities of population variants

Fig. 8

Receiver operating characteristic (ROC) curves showing the degree of misclassification caused by using EP threshold of 0.05 to designate eForbs, when the true EP thresholds for eForbs could be smaller (0.01) or higher (0.1). ROC curves are shown for classification of missense variants found in 1000 Genomes Project Phase 3 dataset using the modified EP approach with both species relationship and divergence times inferred from each sequence alignment. Area under ROC (AUROC) is shown in parentheses, which is similar for different thresholds

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