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Fig. 2 | BMC Evolutionary Biology

Fig. 2

From: Molecular evolutionary and structural analysis of familial exudative vitreoretinopathy associated FZD4 gene

Fig. 2

Domain organization of human Frizzled receptors. Schematic illustration depicts comparative organization of key functional domains and motifs of Frizzled receptor across human paralogs. Protein lengths are drawn approximately to scale. Domains and motifs are color coded. Asterisk symbol indicates the positions of 47 different FEVR causing variants on human FZD4 protein (40 missense variants are indicated with the black asterisk symbol, whereas 7 nonsense variants are depicted by red asterisks)

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