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Table 9 Functional enrichment summary of protein-protein interaction network of proteins evolved with decelerated RSA change rate in Rodentia clade (based on STRING [54] data)

From: mtProtEvol: the resource presenting molecular evolution analysis of proteins involved in the function of Vertebrate mitochondria

Function

Heterotachy model

All data

Protein structure-aware data

FDR

Colora

FDR

Colora

mitochondrial transport

0.000898

green

0.000486

red

oxidation-reduction process

4.89E-05

red

0.000905

blue

carboxylic acid metabolism

0.00953

0.00116

green

small molecule catabolism

0.00953

0.00203

yellow

small molecule metabolism

0.0147

0.00471

violet

ketone body catabolism

0.0147

0.0139

negative regulation of mitochondrion organization

0.0276

0.021

mitochondrion organization

0.000142

blue

single-organism metabolism

0.000898

yellow

cellular respiration

0.00151

violet

organonitrogen compound metabolism

0.0103

mitochondrial translation

0.0147

  1. aprotein colors on the Fig. 9