mtProtEvol: the resource presenting molecular evolution analysis of proteins involved in the function of Vertebrate mitochondria

Table 9 Functional enrichment summary of protein-protein interaction network of proteins evolved with decelerated RSA change rate in Rodentia clade (based on STRING [54] data)

Function	Heterotachy model
	All data		Protein structure-aware data
	FDR	Color^a	FDR	Color^a
mitochondrial transport	0.000898	green	0.000486	red
oxidation-reduction process	4.89E-05	red	0.000905	blue
carboxylic acid metabolism	0.00953	–	0.00116	green
small molecule catabolism	0.00953	–	0.00203	yellow
small molecule metabolism	0.0147	–	0.00471	violet
ketone body catabolism	0.0147	–	0.0139	–
negative regulation of mitochondrion organization	0.0276	–	0.021	–
mitochondrion organization	0.000142	blue	–	–
single-organism metabolism	0.000898	yellow	–	–
cellular respiration	0.00151	violet	–	–
organonitrogen compound metabolism	0.0103	–	–	–
mitochondrial translation	0.0147	–	–	–

ISSN: 2730-7182