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Table 4 Functional enrichment summary of protein-protein interaction network of proteins evolved with accelerated RSA change rate in Rodentia clade (based on STRING [54] data)

From: mtProtEvol: the resource presenting molecular evolution analysis of proteins involved in the function of Vertebrate mitochondria

Function Heterotachy model Heterotachy and Site partitioning models intersection, all data
All data Protein structure-aware data
FDR Colora FDR Colora FDR Colora
mitochondrial ATP synthesis coupled electron transport 0.00036 red 0.00053 green
mitochondrial electron transport, NADH to ubiquinone 0.00147 yellow 0.00053 blue
oxidative phosphorylation 0.00331 0.00053 red
ATP metabolism 0.00399 0.00053 violet
cellular respiration 0.00478 0.00053 yellow
oxidation-reduction 0.00615 0.0389
small molecule metabolism 0.00147 violet 0.0493
catalytic activity 5E-06 red
mitochondrion organization 0.00078 blue
purine ribonucleoside triphosphate metabolism 0.00119 green
single-organism metabolism 0.00147
protein targeting to mitochondrion 0.00258
mitochondrial transport 0.00328
ketone body catabolism 0.00692
nucleotide binding 0.0167 blue
ribonucleotide binding 0.0167 green
purine ribonucleoside binding 0.033 yellow
purine ribonucleotide binding 0.033 violet
  1. aprotein colors on the Fig. 6
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