Skip to main content

Table 2 Functional enrichment summary of protein-protein interaction network of proteins evolved with accelerated RSA change rate in Primata clade (based on GENEMANIA [55] data; see Fig. 6)

From: mtProtEvol: the resource presenting molecular evolution analysis of proteins involved in the function of Vertebrate mitochondria

Function Heterotachy model, FDR Heterotachy and Site partitioning models intersection, all data, FDR
All data Protein structure-aware data
carboxylic acid catabolism 0.000188 2.53E-12 0.000269
organic acid catabolism 0.000188 2.53E-12 0.000269
small molecule catabolism 0.000812 2.32E-11 0.000768
fatty acid beta-oxidation 0.000812 1.46E-11 0.004036
alpha-amino acid metabolism 0.000888 0.000142 0.008642
monocarboxylic acid catabolism 0.00394 1.46E-11 0.009869
mitochondrial matrix 1.37E-14 3.24E-18
mitochondrial nucleoid 9E-06 6.57E-07
mitochondrial membrane 2.82E-06 9.28E-06
water-soluble vitamin metabolism 0.000812 4.74E-06
cellular respiration 5.87E-07 0.001263
mitochondrial inner membrane 0.000888 0.00178
carnitine transmembrane transport 0.003698 0.004036
amino-acid betaine transport 0.004428 0.004036
carnitine transport 0.004428 0.004036
cofactor metabolism 0.002887 0.006798
fatty acid transmembrane transport 0.005223 0.004663
quaternary ammonium group transport 0.00747 0.006053
\