Table 10 Functional enrichment summary of protein-protein interaction network of proteins evolved with decelerated RSA change rate in Rodentia clade (based on GENEMANIA [55] data)
Function | All data, FDR | Protein structure-aware data, FDR |
|---|---|---|
mitochondrial matrix | 3.41E-13 | 1.44E-11 |
mitochondrial transport | 0.000165 | 0.002027 |
mitochondrial membrane | 0.000113 | 0.0022 |
small molecule catabolism | 0.000348 | 0.0022 |
protein homotetramerization | 0.000191 | 0.003698 |
mitochondrion organization | 0.000595 | 0.003698 |
negative regulation of mitochondrion organization | 0.001061 | 0.048293 |
mitochondrial outer membrane | 0.000348 | – |