Table 1 Cytochrome P450 families with the number of genes and their main function
From: Is there adaptation in the human genome for taste perception and phase I biotransformation?
Gene family | Number of genes | Main function |
|---|---|---|
CYP1 | 3 | Biotransformation |
CYP2 | 16 | Biotransformation |
CYP3 | 4 | Biotransformation |
CYP4 | 12 | Fatty acids metabolism |
CYP5 | 1 | Thromboxane A2 synthesis |
CYP7 | 2 | Bile acid biosynthesis |
CYP8 | 2 | Bile acid and prostacyclin biosynthesis |
CYP11 | 3 | Steroid biosynthesis |
CYP17 | 1 | Steroid biosynthesis |
CYP19 | 1 | Steroid biosynthesis |
CYP20 | 1 | Unknown |
CYP21 | 1 | Steroid biosynthesis |
CYP24 | 1 | Vitamin D degradation |
CYP26 | 3 | Retinoic acid hydroxylation |
CYP27 | 3 | Vitamin D3 and bile acid synthesis |
CYP39 | 1 | Cholesterol synthesis |
CYP46 | 1 | Cholesterol synthesis |
CYP51 | 1 | Cholesterol synthesis |