Fig. 4

Example of predictions for disordered regions by PONDR. The X axis represents the protein length; the Y axis shows the score of the predictor VL-XT, which compares two predictors based on neural networks. The higher the value (closer to 1), the most disordered it is. The thick bars show the best predicted disordered regions. The VL-TX algorithm is more accurate for stretches longer than 30 amino acids. Regions shaded in light blue are the signal peptide regions; regions shaded in light orange are the conserved C-terminal regions. a: The glue proteins with internal repeats of D. simulans, except Sgs5; b: example of an Sgs5 protein with large internal repeats (D. kikkawai) compared to the one of D. simulans