Table 1 Summary of NSP gene features

Orphan gene^a

X

X

X

X

X

–

–

Conserved domains

TSP1, LamG3

LamG3

Galectin

CRD

MANEC

Peptidase S8

γ glutamyl transpeptidase

Single copy

–

X

X

–

X

–

–

Previously reported

–

X (nb012)

–

–

–

X

X

Signal peptide in NSP

X

X

X

X

–

X

–

Transmembrane domain

–

–

–

–

X

–

X

Protein category^b

Structural

Structural

Structural

Novel

Novel

Serine peptidase

Metabolic enzyme glutamate

Shell Protein^b

X

X

–

X

–

–

X

Higher copy number in Hydrozoa compared to anthozoans

–

–

X

–

–

X

–

Present in C. shasta polar capsule proteome

X

X

X

–

–

X

X

Cnidarian clades found to possess the gene

Anthozoa

Medusozoa

Myxozoa

Anthozoa

Medusozoa

Myxozoa

Polypodium

Medusozoa

Myxozoa

Polypodium

Anthozoa

Medusozoa

Myxozoa

Polypodium

Anthozoa

Medusozoa

Myxozoa

Polypodium

Anthozoa

Medusozoa

Myxozoa

Polypodium

Anthozoa

Medusozoa

Myxozoa

Polypodium