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Table 1 Ovarian cancer cell lines, selection and culture conditions

From: Cysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer

Cell line- histological type

Cell line code

Selection condition

Culture condition

Ovarian clear cell carcinoma (OCCC; ES2)

ES2-AN

Non selected ancestral cell line

Normoxia

ES2-ANC

Non selected ancestral cell line

Normoxia + cysteine

ES2-AH

Non selected ancestral cell line

Hypoxia

ES2-AHC

Non selected ancestral cell line

Hypoxia + cysteine

ES2-NN

Selected under Normoxia

Normoxia

ES2-NNC

Selected under Normoxia

Normoxia + cysteine

ES2-NH

Selected under Normoxia

Hypoxia

ES2-NHC

Selected under Normoxia

Hypoxia + cysteine

ES2-HN

Selected under Hypoxia

Normoxia

ES2-HNC

Selected under Hypoxia

Normoxia + cysteine

ES2-HH

Selected under Hypoxia

Hypoxia

ES2-HHC

Selected under Hypoxia

Hypoxia + cysteine

Ovarian serous carcinoma (OSC; OVCAR3)

OVCAR3-AN

Non selected ancestral cell line

Normoxia

OVCAR3-ANC

Non selected ancestral cell line

Normoxia + cysteine

OVCAR3-AH

Non selected ancestral cell line

Hypoxia

OVCAR3-AHC

Non selected ancestral cell line

Hypoxia + cysteine

OVCAR3-NN

Selected under Normoxia

Normoxia

OVCAR3-NNC

Selected under Normoxia

Normoxia + cysteine

OVCAR3-NH

Selected under Normoxia

Hypoxia

OVCAR3-NHC

Selected under Normoxia

Hypoxia + cysteine

OVCAR3-HN

Selected under Hypoxia

Normoxia

OVCAR3-HNC

Selected under Hypoxia

Normoxia + cysteine

OVCAR3-HH

Selected under Hypoxia

Hypoxia

OVCAR3-HHC

Selected under Hypoxia

Hypoxia + cysteine