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Fig. 5 | BMC Evolutionary Biology

Fig. 5

From: Whole genome duplications have provided teleosts with many roads to peptide loaded MHC class I molecules

Fig. 5

A visual summary of the complexity in number of genes involved in MHCI peptide cleavage, peptide transport, peptide loading and editing in Atlantic salmon. Endoplasmatic reticulum (ER) lumen and cytosolic compartments are shown. Number of Atlantic salmon genes per each human gene ortholog is shown using red font. Like (L) extensions are used when Atlantic salmon sequences exist in duplicates with one groups clustering closer to the human ortholog than the gene-like sequences. Black arrows indicate movement through the compartments while red arrows point to location of molecules

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