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Table 2 Selected KEGG pathways significantly enriched for down-regulated genes in sugar-only diet (SD) versus normal diet (ND)

From: Phenotypes, antioxidant responses, and gene expression changes accompanying a sugar-only diet in Bactrocera dorsalis (Hendel) (Diptera: Tephritidae)

KEGG pathway

Pathway ID

DEGs (1229)

P-value

Level 1

Level 2

Cell cycle

ko04110

49 (3.99%)

9.25e-19

Cellular Processes

Cellular Processes

DNA replication

ko03030

28 (2.28%)

1.66e-16

Genetic Information Processing

Replication and repair

Cell cycle - yeast

ko04111

39 (3.17%)

4.57e-13

Cellular Processes

Cell growth and death

Meiosis - yeast

ko04113

28 (2.28%)

1.22e-08

Cellular Processes

Cell growth and death

Mismatch repair

ko03430

14 (1.14%)

3.69e-07

Genetic Information Processing

Replication and repair

RNA transport

ko03013

51 (4.15%)

5.08e-07

Genetic Information Processing

Translation

Nucleotide excision repair

ko03420

19 (1.55%)

2.27e-06

Genetic Information Processing

Replication and repair

Ubiquitin mediated proteolysis

ko04120

36 (2.93%)

7.68e-06

Genetic Information Processing

Folding, sorting and degradation

Progesterone-mediated oocyte maturation

ko04914

24 (1.95%)

1.55e-05

Organismal Systems

Endocrine system

Fanconi anemia pathway

ko03460

14 (1.14%)

0.000144

Genetic Information Processing

Replication and repair

Protein processing in endoplasmic reticulum

ko04141

34 (2.77%)

0.00165

Genetic Information Processing

Folding, sorting and degradation

Spliceosome

ko03040

35 (2.85%)

0.00193

Genetic Information Processing

Transcription

mTOR signaling pathway

ko04150

5 (0.41%)

0.00423

Environmental Information Processing

Signal transduction

mRNA surveillance pathway

ko03015

22 (1.79%)

0.0101

Genetic Information Processing

Translation

p53 signaling pathway

ko04115

12 (0.98%)

0.0124

Cellular Processes

Cell growth and death

Oocyte meiosis

ko04114

23 (1.87%)

0.0131

Cellular Processes

Cell growth and death

Insulin signaling pathway

ko04910

18 (1.4%)

0.0154

Organismal Systems

Endocrine system

RNA degradation

ko03018

19 (1.55%)

0.03263363

Genetic Information Processing

Folding, sorting and degradation

ErbB signaling pathway

ko04012

15 (1.22%)

0.03373181

Environmental Information Processing

Signal transduction

Insect hormone biosynthesis

ko00981

11 (0.9%)

0.03590656

Metabolism

Metabolism of terpenoids and polyketides

  1. The Bonferroni correction method was used for multiple hypothesis test correction and FDR-corrected P < 0.05 as cut-off