Fig. 3

Paralogous blocks descended from the two whole genome duplication events that happened prior to the emergence of bony vertebrates. The localization of the genes is illustrated with a grey line and the paralogons have the same color. a A region on an ancestral chromosome was duplicated and can in humans be found in chromosome 3, 1 and 17 in which p63, p73 and p53 are localized, respectively. b A region on an ancestral chromosome was duplicated and can in humans be found in chromosome 1 and 12 where MDM2 and MDM4 are localized, respectively [18]