Skip to main content

Table 3 Introgressed indels linked to genome-wide association studies candidates

From: Using the Neandertal genome to study the evolution of small insertions and deletions in modern humans

Chr Indel pos. SNP pos. SNP rs ID P-value Trait EAS_AF EUR_AF Gene C-score(indel) Ref.
1 196,365,712 196,376,474 rs16839886 7.26E-06 Age-related macular degeneration 0.0129 0.0746 KCNT2 8.613 [59]
1 209,987,712 209,988,047 rs10863790 1.00E-14 Cleft lip 0.4286 0.0139 NA 4.657 [60]
1 210,174,981 210,174,417 rs11119388 4.57E-09 Cleft lip 0.4454 0.0089 SYT14 9.739 [60]
14 55,769,446 55,808,151 rs17673930 1.89E-40 Protein biomarker 0.006 0.0805 CHMP4BP1 6.577 [61]
2 157,099,707 157,096,776 rs17188434 1.00E-09 Menarche (age at onset) 0.0099 0.0606 NA 6.499 [36]
3 23,386,162 23,385,942 rs17013049 2.78E-06 Type 2 diabetes 0.1131 0.0239 UBE2E2 6.473 [62]
3 100,671,648 100,647,927 rs13060137 8.96E-08 Suicide attempts in bipolar disorder 0.002 0.1531 RNU6-865P 3.313 [63]
8 20,253,488 20,263,408 rs1016646 9.45E-06 Preeclampsia 0.0923 0.0636 NA 2.605 [59]
9 87,171,753 87,177,586 rs35640669 5.17E-08 Insulin-related traits 0.0546 0.0348 NA 0.207 [64]
  1. EAS AF East Asian allele frequency;EUR AF European allele frequency