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Table 1 Nonsynonymous (dN) and synonymous (dS) substitutions (± standard error) and their ratio in ABS and non-ABS for MHCI and MHCII-DRB sequences

From: Retention of functional variation despite extreme genomic erosion: MHC allelic repertoires in the Lynx genus

  ABS non-ABS ABS vs non-ABS
     Species dN dS dN/dS P dN dS dN/dS P dS.ABS/dS.non-ABS P
MHCI (17/59)
     Total 0.26 ± 0.022 0.6 ± 1.39 0.43 n.s 0.06 ± 0.001 0.08 ± 0 0.73 *** 7.706 ***
      L. pardinus 0.3 ± 0.027 0.68 ± 2.35 0.44 * 0.07 ± 0.001 0.1 ± 0.01 0.76 n.s 6.972 ***
      L. lynx 0.26 ± 0.022 0.43 ± 1.36 0.59 n.s 0.06 ± 0.001 0.08 ± 0 0.73 * 5.443 ***
      L. canadensis 0.28 ± 0.024 0.68 ± 1.23 0.4 ** 0.06 ± 0.001 0.09 ± 0 0.67 ** 7.466 ***
      L. rufus 0.33 ± 0.032 1.01 ± 1.55 0.33 n.s 0.08 ± 0.002 0.1 ± 0.01 0.81 n.s 9.89 ***
MHCII-DRB (24/58)
     Total 0.19 ± 0.011 0.17 ± 0.03 1.09 n.s 0.06 ± 0.001 0.13 ± 0.01 0.46 *** 1.354 **
      L. pardinus 0.14 ± 0.008 0.16 ± 0.03 0.88 n.s 0.06 ± 0.001 0.14 ± 0.01 0.4 *** 1.166 n.s
      L. lynx 0.16 ± 0.009 0.15 ± 0.02 1.1 n.s 0.06 ± 0.001 0.14 ± 0.01 0.43 *** 1.057 n.s
      L. canadensis 0.19 ± 0.011 0.2 ± 0.03 0.99 n.s 0.07 ± 0.002 0.16 ± 0.01 0.48 n.s 1.251 n.s
      L. rufus 0.26 ± 0.016 0.23 ± 0.03 1.11 n.s 0.07 ± 0.001 0.12 ± 0.01 0.59 * 1.907 **
  1. The number of amino acids in each typology appears in brackets (ABS/non-ABS). dN is the number of nonsynonymous substitutions and dS the number of synonymous substitutions per site category (ABS or Non-ABS). P is the probability (using a Mann-Whitney U-test) that dN and dS are different at each site type or that dS differ between ABS and Non-ABS