From: Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes
Foreground branch | BEB sites | Homologous position in cow paralog | Function known from homologs | SDP? |
---|---|---|---|---|
ARR0.1 sea urchins | S76 | N83 | Second neighboring to receptor binding residue | x |
E95 | E102 | - | x | |
K116 | K157 | Low affinity IP6 binding site | x | |
N121 | N162 | Neighboring to low affinity IP6 binding site | x | |
N184 | N225 | Second neighboring to receptor binding residue | - | |
C201 | C242 | Receptor binding | x | |
N296 | N382 | Second neighboring to clathrin binding site | - | |
ARR0.2 sea urchins | K82 | P89 | Neighboring to PxxP motif | - |
SAG.1 ghost shark | K2 | K2 | - | na |
V106 | P134 | Neighboring to receptor binding residue | na | |
N114 | R171 | Phosphate sensor | na | |
T128 | G185 | Neighboring to PxxP motif | na | |
N160 | G217 | - | na | |
H205 | E262 | Receptor binding | na | |
Q248 | N305 | Second neighboring to polar core | na | |
V277 | T334 | Second neighboring to high affinity IP6 binding site | na | |
S27 | G27 | Second neighboring to receptor binding residue | na | |
SAGb teleost | V14 | V35 | Second neighboring to polar core | x |
R126 | W194 | Receptor binding | - | |
SAGb Acanthopterygii | P72 | P93 | Neighboring to PxxP motif | na |
A112 | A180 | Neighboring to PxxP motif | na | |
D142 | S210 | - | na | |
ARR3b Euteleosteomorpha | Y42 | M55 | Neighboring to mu2 adaptin binding site | x |
C150 | F254 | Neighboring to receptor binding residue | x |