Fig. 4

a Survivorship of rotifers treated with estrogen-like receptor binding small molecules. b manjavacas neonates were treated with 10 μM of each compound for the duration of their life. No significant changes in lifespan were observed in the treated animals when compared to animals grown without ligands. b AMI ligands do not negatively affect the reproductive rate of rotifers. The effects of ER binding AMI molecules on rotifer reproduction are shown above. AB-89 significantly increased reproduction compared to the control group. Exposure to ER binding AMI molecule AB-89 at 10 μM significantly increased by 38%. The average reproductive rate for B. manjavacas reproduction increased from 18 to 24 offspring per female