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Table 3 Association of G6PC2 variants with T2D

From: Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection

Sample/SNP (Variant) Genotype frequency Minor/Major allele Minor allele freq (%) Corrected p value OR (IC 95%) Corrected p value OR (IC 95%)
       Unconditional Conditional on rs560887
rs560887, intronic, (GWAS)
  CC CT TT       
 Diabetic cohort 0.643 0.319 0.038 T/C 19.7 0.368 1.23 (0.78–1.95) - -
 Control cohort 0.679 0.276 0.045   18.3     
rs492594 (p.Val219Leu)
  GG GC CC       
 Diabetic cohort 0.334 0.475 0.19 C/G 42.9 0.099 1.50 (1.03–2.18) 0.018 1.70 (1.14–2.54)
 Control cohort 0.368 0.483 0.149   39.1     
rs2232328 (p.Ser342Cys)
  CC CG GG       
 Diabetic cohort 0.619 0.299 0.081 G/C 23.1 0.099 1.51 (0.97–2.36) 0.034 1.64 (1.04–2.58)
 Control cohort 0.688 0.274 0.038   17.5