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Table 1 Average non-synonymous/synonymous substitution rate ratio (dN/dS) and percentage of negatively selected sites fot the three G6Pase genes

From: Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection

Gene

ALIAS

Protein size (amino acids)

Tree Lenght

N° of species

Average dN/dS (95% confidence intervals)

% of FEL negatively selected sites

G6PC

G6PT

357

8.65

64

0.167 (0.156, 0.178)

66.39%

G6PC2

IGRP

355

6.44

64

0.206 (0.191, 0.222)

52.11%

G6PC3

UGRP

346

7.62

62

0.159 (0.147, 0.171)

66.18%