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Table 5 Annotation of the ± 10 genomic neighborhood of gene SCO7691 from S. coelicolor

From: Assessing in silico the recruitment and functional spectrum of bacterial enzymes from secondary metabolism

BGC0000315; SM* sco:SCO3214 Anthranilate synthase component 1 (EC 4.1.3.27) ↔ SC4C2.26; lyase; K04781 salicylate synthetase; E-value 7.0E-36

E_PM

K_SM

KEGG Annotation

Pathways in ±10/±2 Nh

  

sco:SCO7681; AMP-binding ligase

2/1 sco01053 Biosynthesis of siderophore group

1/1 sco01130 Biosynthesis of antibiotics

1/1 sco01110 Biosynthesis of secondary metabolites

1/0 sco00562 Inositol phosphate metabolism

  

sco:SCO7682; non-ribosomal peptide synthase

  

sco:SCO7683; non-ribosomal peptide synthase

  

sco:SCO7684; hypothetical protein

  

sco:SCO7685; hypothetical protein

  

sco:SCO7686; cytochrome P450

  

sco:SCO7687; thioesterase

  

sco:SCO7688; hypothetical protein

  

sco:SCO7689; ABC transporter ATP-binding protein

  

sco:SCO7690; ABC transporter ATP-binding protein

 

S

sco:SCO7691; lyase; K04781 salicylate synthetase

  

sco:SCO7692; hypothetical protein

  

sco:SCO7693; oxidoreductase

  

sco:SCO7694; TetR family transcriptional regulator

  

sco:SCO7695; hypothetical protein

  

sco:SCO7696; MarR family transcriptional regulator

  

sco:SCO7697; hydrolase; K01083 3-phytase (EC 3.1.3.8)

  

sco:SCO7698; MerR family transcriptional regulator

  

sco:SCO7699; nucleotide-binding protein

  

sco:SCO7700; cyclase; (EC:4.2.3.118)

  

sco:SCO7701; methyltransferase; (EC:2.1.1.255)

  1. The first line gives the name of the MIBiG cluster containing the considered SM* enzyme, the annotation of the SM* and the related putative PM enzyme from the same genome, and the BLAST E-value resulting from the comparison of the corresponding two protein sequences
  2. The following lines characterize the ±10 genomic neighbourhood of the putative PM enzyme. A “P” in column “E_PM” indicates that this enzyme function, i. e. EC number, occurs in enzymes PM* and an “S” in column “K_SM” indicates that KEGG assigned this enzyme function to the pathway “Biosynthesis of secondary metabolites”. The column named “KEGG Annotation” lists KEGG-ID, function and EC number of the gene products. The column named Pathways in ±10/±2 Nh” lists the number of genes from the corresponding two neighborhoods of the putative PM enzyme that belong to the listed KEGG pathways. For this table, the gene annotations taken from the respective html-page were shortened for the sake of brevity
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BMC Ecology and Evolution

ISSN: 2730-7182

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