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Table 1 Conserved retinoic acid response elements (RAREs) with the characteristic sequence signature AGTTCA(N)5AGTTCA identified in the vicinity of bilaterian CYP26 genes

From: Lineage-specific duplication of amphioxus retinoic acid degrading enzymes (CYP26) resulted in sub-functionalization of patterning and homeostatic roles

Species

RARE name

Orientation relative to the CYP26 gene

Sequence (5′–3′)

Upstream of

Distance to start codon

Reference

S.p.

 

+

AGTTCAATAGTTCA

CYP26

2503 bp

This study

S.k.

 

-

AGTTCATACCCAGTTCA

CYP26a

137 bp

This study

B.f.

DR5-6

-

AGTTCAACAAAAGTTCA

CYP26-2

6405 bp

This study

B.b.

DR5-6

-

AGTTCAACAAAAGTTCA

CYP26-2

6740 bp

This study

B.l.

DR5-6

-

AGTTCAACAAAAGTTCA

CYP26-2

4083 bp

This study

H.s.

R1

-

AGTTCACCCAAAGTTCA

CYP26A1

132 bp

[26]

M.m.

R1

-

AGTTCACCCAAAGTTCA

CYP26A1

134 bp

[26]

D.r.

R1

-

AGTTCACACAAAGTTCA

CYP26A1

166 bp

[26, 54]

R2

-

AGTTCAAGGATAGTTCA

CYP26A1

1963 bp

T.r.

R1

-

AGTTCATTCAAAGTTCA

CYP26A1

103 bp

This study

  1. Species name abbreviations: B.b. Branchiostoma belcheri, B.f. Branchiostoma floridae, B.l. Branchiostoma lanceolatum, D.r. Danio rerio, H.s. Homo sapiens, M.m. Mus musculus, S.k. Saccoglossus kowalevskii, S.p. Strongylocentrotus purpuratus, T.r. Takifugu rubripes