Fig. 2
From: Evolution of the angiopoietin-like gene family in teleosts and their role in skin regeneration
Phylogenetic tree of the fish Angptl with the tetrapod and cephalochordate homologues. Tree was constructed with the Bayesian interference (BI) built in MrBayes 3.2 and branch support values (posterior probability values) are shown only for the major protein family clades. The Angptl family clusters are boxed with different colours. The phylogenetic tree is compacted and was generated from the original tree available in Additional file 2: Figure S1. The tree was rooted using the deuterostome Angpt clade (Angpt1, Angpt2 and Angpt4) but details are not show in the figure to facilitate interpretation. For the same reason, the detailed presentation of the teleost and tetrapod members of each family group have been collapsed. A tree with similar topology was obtained using the Maximum-likelihood algorithm and 100 bootstrap replicates (Additional file 3: Figure S2). ANGPTL8 was not included in the phylogenetic analysis as it is an atypical family member and lacks the FReD domain