Fig. 5

Trade-offs in the resistance potential between the gene regulatory network and receptor proteins. For the susceptible host population, the ability to resist using a GRN rewiring and b protein binding site changes is measured for different receptor binding complexities (Error bar: std. dev. over 100 simulations). As the receptor binding complexity increases, hosts increase evolutionary potential more on the GRN while decreasing it on receptor proteins (μ _hp  = 0.01, N _ER /N _R  = 3/5, ϵ _seqM  = 90 %, k _I  = 0.8)