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Table 3 Non-synonymous (dN) and synonymous (dS) substitutions (± standard deviation) for C. perspicillata, D. rotundus and M. molossus

From: Spatial pattern of genetic diversity and selection in the MHC class II DRB of three Neotropical bat species

Species Region N dN ± SD dS ± SD dN/dS Z-test p-value
C. perspicillata
  ABS 25 0.405 ± 0.131 0.082 ± 0.064 4.939 5.119 <10-5
  Non-ABS 64 0.121 ± 0.047 0.043 ± 0.029 2.792 3.283 0.0013
  All 89 0.187 ± 0.053 0.0528 ± 0.026 3.548 5.619 <10-5
D. rotundus
  ABS 25 0.314 ± 0.116 0.077 ± 0.055 4.081 3.811 0.0002
  Non-ABS 64 0.049 ± 0.035 0.045 ± 0.032 1.075 0.156 0.8764
  All 89 0.114 ± 0.470 0.054 ± 0.032 2.119 2.713 0.0077
M. molossus
  ABS 21 0.323 ± 0.103 0.068 ± 0.058 4.753 4.080 0.0001
  Non-ABS 60 0.060 ± 0.021 0.056 ± 0.031 1.078 0.186 0.8528
  All 81 0.120 ± 0.028 0.058 ± 0.030 2.049 2.599 0.0105
  1. Putative ABS and non-ABS were identified assuming functional homology to the human ABS of the HLA-DR1 molecule Brown et al. [65]. N is the number of codons in each sequence region. Z-test values and p-values are shown