Fig. 2From: Spatial pattern of genetic diversity and selection in the MHC class II DRB of three Neotropical bat speciesAmino acid sequence variation and overall frequency of MHC class II DR beta exon 2 alleles of C. perspicillata, D. rotundus and M. molossus. DRB sequences of Homo sapiens (accession number: NG_29921), C. perspicillata (Cape-DRB*01, accession number: JQ388830), N. albiventris (Noal-DRB*01, accession number: HM347941) and A. jamaicensis (Arja-DRB*01, accession number: KJ010995) are given for comparison. Antigen-binding sites (ABS) of the HLA-DRB1 molecule are shadowed [65]. Dots mark identity with the top sequence. Numbers in italics indicate the amino acid positions within the beta 1 domain of the HLA-DRB1 molecule. Asterisks indicate the positively selected sites (PSS) identified in each species, according to acceptance criteria described in the Methods section [68]. †indicates PSS identified by [35], and ‡ indicates PSS identified by [38]Back to article page