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Fig. 2 | BMC Evolutionary Biology

Fig. 2

From: Why and how genetic canalization evolves in gene regulatory networks

Fig. 2

Evolution of canalization. Genes under direct and indirect selection pressures evolved differently. a Evolution of gene expression. Blue: selected genes (two out of six genes in the network); red: unselected genes; black: control simulations (no selected genes). The horizontal dotted line stands for the selected expression level. Filled areas stand for the s.d. across 200 replicates, illustrating the amount of stochasticity in the simulations. Statistics were measured every 500 generations. b Evolution of canalization score C i (negative log of the variance of mutational effects). c Distribution of gene expression values S i at the last generation (G=10,000). d Distribution of regulatory effects (W ij ) at the last generation (immutable 0s are discarded from the analysis). The vertical dotted line stands for the absence of regulation

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