Fig. 9

Evolution of alternative splicing for SMRT and NCoR. A dendrogram representation of evolutionary divergence is presented for the species analyzed at the alternatve splice sites previously reported. Dashed lines indicates use of different time scale for the Drosophila divergence. The postulated gain (green symbols) or loss (red symbol) of each alternative splicing site is depicted near the base of the relevant lineages (S = SMRT and N = NCoR]. A tissue-specific dendrogram would differ only by the absence of detectable S40 alternative splicing in Danio tissues other than brain and whole 84 h. hatchlings; otherwise the different tissues within a given species vary in the abundance of the alternative spliced variants noted here, but not in their presence or absence