Table 2 Promoter elements common to HAP1 gene promoters of all tested eutherian mammals, and 0, 1 or both tested marsupials
Matrix ID | Description | Function | |
|---|---|---|---|
Present in Eutherians (6/6) AND Marsupials (2/2) | O$VTATA.01 | Cellular and Viral TATA box elements | Transcription initiation complex |
O$MTATA.01 | Vertebrate TATA binding protein factor (muscle) | Transcription initiation complex | |
V$CDX1.02 | Caudal-type homeobox 1 | Differentiation | |
V$CDX2.02 | Caudal-type homeobox 2 | Differentiation | |
V$MAX.03 | MYC-associated factor X | Cell cycle | |
V$WT1.01 | Wilms tumour suppressor | Cell cycle | |
V$E2F.02 | E2F, MYC activator | Cell cycle | |
Present in Eutherians (6/6) but NOT Marsupials (0/2) | V$XCPE.01 | X gene core promoter element | Core promoter element/Enhancer |
V$ZF5.01 | Zinc finger/POZ domain transcription factor | Not yet established | |
V$ZF5.02 | ZF5 POZ domain zinc finger, zinc finger protein 161 | Not yet established | |
V$E2F.03 | E2F, MYC activator | Cell-cycle | |
V$NGFIC.01 | Nerve Growth Factor-induced Protein C (EGR4) | Growth | |
Present in Eutherians (6/6) and ONE Marsupial (1/2) | V$ATF6.01 | Member of b-zip family, induced by ER damage/stress | ER Stress response |
V$E2F6.01 | E2F Transcription factor 6 | Cell cycle | |
V$E2F7.02 | E2F Transcription factor 7 | Cell cycle | |
V$EGR1.03 | Early Growth Response 1 | Growth | |
V$GRHL1.01 | Grainyhead-like | Differentiation/development | |
V$LRRFIP1.01 | Leucine-rich repeat (in FlII) Interacting Protein | Cell cycle | |
V$MAZR.01 | MYC-associated zinc finger protein related factor | Cell cycle | |
V$NRF1.01 | Nuclear Respiratory Factor 1 | Mitochondrial energy production | |
V$ZNF219.01 | Kruppel-like Zinc finger binding protein 219 | Differentiation/development |