Gene symbol (Gene name description) | Gene product | Description | E value (<0.1) | |
---|---|---|---|---|
Common Hits | fimC (FIMbrin) | Fimbrin-3 | Actin binding protein with 4 calponin homology domains | TRAK1: 2×10−6 Milton: 2×10−4 |
mhcA (Myosin Heavy Chain A) | Myosin II heavy chain | Myosin II heavy chain, component of the actin-based molecular motor (conventional myosin); has actin-activated ATPase activity; | TRAK1:7×10−3 Milton: 3×10−4 | |
DDB_G0290503 | DDB0346607 | Hypothetical protein predicted to be involved in meiosis and the synaptonemal complex | TRAK1: 5×10−5 Milton: 0.011 | |
fimD (FIMbrin) | Fimbrin-4 | Actin binding protein with 4 calponin homology domains | TRAK1: 0.001 Milton: 0.079 | |
kif4 (KInesin Family member 4) | Kinesin family member 4 | Member of the CENP-E subfamily, predicted to play a role in mitosis | TRAK1: 0.01 Milton: 0.055 | |
DDB_G0289761 | DDB0348198 | Not yet annotated | TRAK1: 0.051 Milton: 0.013 | |
Additional TRAK1 hits | myoJ (MYOsin) | myosin-5b | Conditional processive motor protein that can move over long distances along F-actin without disassociating | 0.001 |
smc1 (Structural Maintenance of Chromosome) | structural maintenance of chromosome protein | Functions in chromosome dynamics | 0.021 | |
zipA (ZIPper) | zipper-like domain-containing protein | - | 0.022 | |
kif9 (KInesin Family member 9) | Kinesin family member 9 | Plays a role in connecting the centrosome with the nucleus | 0.067 | |
kif1 (KInesin Family member 1) | Kinesin-3 | Kinesin family member 1; ortholog of C. elegans Unc104 and mammalian KIF1A, involved in intracellular transport | 0.09 | |
DDB_G0287325 | AP2 complex protein Eps15 | Similar to mammalian EPS15, a clathrin adaptor that binds to the AP2 alpha subunit in mammalian cells | 0.033 | |
DDB_G0288073 | Nucleoprotein TPR | - | 0.016 | |
DDB_G0271334 | C2 calcium/lipid-binding (CaLB) region and dilute domain-containing protein | Contains a dilute domain, found at the carboxyl terminus of non-muscle myosin V | 0.061 | |
Additional Milton hits | rad50 (Similar to RADiation sensitive mutant) | DNA recombination/repair protein | Similar to S. cerevisiae RAD50, involved in processing double-strand DNA breaks with Mre11. | 0.001 |
sun1 (Sad1p and UNC-84) | SUN domain-containing protein 1 | Localizes to the inner and outer nuclear membrane, mediates the attachment between centrosome and nucleus, associates the centromere cluster with the centrosome, and stabilizes the genome during mitosis; contains one transmembrane domain | 0.008 | |
ndm (Negative director of macropinocytosis) | macropinocytosis suppressor Ndm | Contains a coiled-coil, C-terminal BAR-like domain | 0.014 | |
hook | hook family protein | Similar to C. elegans ZYG-12 and mammalian HOOK proteins, which mediate the attachment between the centrosome and the nucleus | 0.023 | |
abpD (Actin Binding Protein) | Actin-binding protein D | Actin binding protein that is developmentally and cAMP-regulated; associates with intracellular membranes | 0.086 | |
DDB_G0285767 | DDB0347641 | Not yet annotated | 0.003 | |
DDB_G0346831 | DDB0346834 | Not yet annotated | 0.014 |