Skip to main content

Table 1 Presence/absence of enzymes involved in the biosynthesis of heme

From: Heme pathway evolution in kinetoplastid protists

  ALAS gltX GTR (HemA) GSA-AT (HemL) ALAD (HemB) PBGD (HemC) UROS (HemD) UROD (HemE) CPOX (HemF) CPOX (HemN) PPOX (HemY) PPOX (HemG) FeCH (HemH)
Naegleria Naegleria gruberi   +   +       +    +
Euglenida Eutreptiella gymnastica + + + + + + + + + + +   +
Diplonemida Diplonema papillatum *              
Prokinetoplastina putative Perkinsela sp. from Paramoeba atlantica   +            
putative Perkinsela sp. from Neoparamoeba aestuarina + +    + +   + +   +   +
Perkinsela sp. from P. pemaquidensis CCAP1560 + +    + +   + +   +   +
Perkinsela sp. from P. invadens + +    + +   + +   +   +
Neobodonida Neobodo designis   +            
Eubodonida Bodo saltans   +            
Trypanosoma Trypanosoma brucei TREU927   +            
Trypanosoma congolense IL3000   +            
Trypanosoma cruzi CL Brener Esmeraldo-like   +            
Trypanosoma cruzi CL Brener Non-Esmeraldo-like   +            
Trypanosoma cruzi marinkellei B7   +            
Trypanosoma evansi STIB805   +            
Trypanosoma grayi ANR4   +            
Trypanosoma rangeli SC58   +            
Trypanosoma vivax Y486   +            
Phytomonas Phytomonas Hart1   +            +
Phytomonas EM1   +            +
Strigomonadinae Strigomonas culicis   +        +    + +
Angomonas deanei   +        +    + +
Leishmaniinae Leptomonas pyrrhocoris   +        +    + +
Crithidia fasciculata CfCl   +      +   +    + +
Leishmania braziliensis MHOMBR75M2904   +      +   +    + +
Leishmania donovani BPK282A1   +      +   +    + +
Leishmania infantum JPCM5   +      +   +    + +
Leishmania major Friedlin   +      +   +    + +
Leishmania mexicana MHOMGT2001U1103   +      +   +    + +
Leishmania tarentolae ParrotTarII   +      +   +    + +
Amoebozoa Paramoeba pemaquidensis (host) + +    +   + +   + +   
Neoparamoeba aesturina (host) + +    + + + + + +    +
Paramoeba atlantica (host) + +    +   + + + + +   
  1. A ‘+’ indicates the presence of this enzyme. A ‘*’ indicates uncertainty associated with incomplete genomic or transcriptomic data. Blanks indicate protein absence or not detected